In this edited volume, experts on the treatment of dementia associated with Parkinson's Disease (PD) describe in detail the current status of knowledge in their respective area of expertise. The importance and clinical relevance of cognitive impairment and dementia in PD is emphasized, all relevant aspects including epidemiology, full and detailed spectrum of clinical features, current knowledge on pathology, neurochemistry and genetics, findings in auxillary investigations, relation to other neurodegenerative disorders, diagnostic process and management are described, rounded-up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and is heavily referenced thereby capturing all relevant literature.
1. Introduction ; 2. Epidemiology of dementia associated with Parkinson's disease ; 3. General features, mode of onset and course of dementia in Parkinson's disease ; 4. Cognitive profile in Parkinson's disease dementia ; 5. Neuropsychiatric symptoms in Parkinson's disease dementia ; 6. Interaction between affect and executive functions in Parkinson's disease ; 7. Motor symptoms and phenotype in patients with Parkinson's disease dementia ; 8. Interaction between cognition and gait in patients with Parkinson's disease ; 9. Disorders of sleep and autonomic function in Parkinson's disease dementia ; 10. Structural and functional neuroimaging in patients with Parkinson's disease dementia ; 11. Biomarkers for cognitive impairment and dementia in Parkinson's disease ; 12. Electrophysiological and other auxiliary investigations in patients with Parkinson's disease dementia ; 13. Genetic basis of dementia in Parkinson's disease ; 14. Neurochemical pathology of Parkinson's disease dementia and dementia with Lewy bodies ; 15. Pathological correlates of dementia in Parkinson's disease ; 16. Epidemiology, diagnosis and correlates of Mild Cognitive Impairment in Parkinson's disease ; 17. The pathophysiological and prognostic heterogeneity of Mild Cognitive Impairment in Parkinson's disease ; 18. Spectrum of Lewy body dementias: relationship of Parkinson's disease dementia to dementia with Lewy bodies ; 19. Spectrum of disorders with dementia and Parkinsonism ; 20. Diagnosis of dementia in Parkinson's disease ; 21. Management of Parkinson's disease, dementia and dementia with Lewy bodies ; 22. Parkinson's disease: what will the future bring?