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Human Vaccines: Emerging Technologies in Design and Development


Human Vaccines: Emerging Technologies in Design and Development

Paperback by Modjarrad, Kayvon (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health); Koff, Wayne C. (President & CEO, Human Vaccines Project, New York City)

Human Vaccines: Emerging Technologies in Design and Development

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ISBN:
9780128023020
Publication Date:
14 Oct 2016
Language:
English
Publisher:
Elsevier Science Publishing Co Inc
Imprint:
Academic Press Inc
Pages:
186 pages
Format:
Paperback
For delivery:
Estimated despatch 17 - 22 May 2024
Human Vaccines: Emerging Technologies in Design and Development

Description

Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics-among other disciplines-that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology.

Contents

Part I: Designing Vaccines From a New Starting Point Chapter 1. Broadly Neutralizing Antibodies Part II: Pathogen Free Vaccines Chapter 2. Replication-Competent Viral Vectors for Vaccine Delivery Chapter 3. Reverse Vaccinology: Exploiting Genomes for Vaccine Design Chapter 4. Virus-Like Particle and Nanoparticle Vaccines Part III: Immune Monitoring Chapter 5. Systems Vaccinology Chapter 6. Immunogenetics and Vaccination Part IV: Advanced Vaccine Development Chapter 7. Methodical Considerations Chapter 8. Vaccine Development in Special Populations

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